Completely Useless Mouse
This prank is ideal because it is subtle while being irritating enough to really grind your coworker’s gears. Simply place a small Post-It note on the underside of their mouse over the optical sensor, and you’ve got yourself a mouse that doesn’t operate! It’s much better if you write a nasty comment on the Post-It to be found later.
Don’t Cry Over Spilled Milk
For this prank, squirt some Elmer’s glue onto a pan and place it in the freezer. Once the glue has frozen, remove it from the pan and set it on your coworker’s laptop keyboard with a cup next to it to simulate spilled milk. Caution: the adhesive will thaw fast, so finish the prank as soon as you take it out of the freezer! You don’t want to destroy anyone’s property or make someone weep (unless you’re a jerk).